Man struck and killed by semi on Highway 99 overpass in Fresno
A man in his 50s was killed on the Highway 99 overpass at Fresno Street, shutting down a key Fresno corridor and renewing questions about pedestrian danger near the freeway.

A man in his 50s was struck and killed by a semi on the northbound Highway 99 overpass at Fresno Street in downtown Fresno, and the crash quickly tied up one of the city’s most important traffic connections. Fresno police said officers responded to the vehicle-versus-pedestrian collision around 3:40 p.m. Wednesday and pronounced the victim dead at the scene.
The victim was not identified by name, and investigators had not said why he was on the overpass. The case remained open as traffic crews and officers worked through the aftermath on a stretch of State Route 99 that moves commuters, freight and drivers between central Fresno and nearby neighborhoods.
Caltrans warned of delays shortly before the crash was fully reported, a reminder of how fast a fatal incident on Highway 99 can ripple through Fresno County. The corridor between Clinton Avenue and Ashlan Avenue carries an average of 114,000 vehicles a day, and trucks make up 17% of that traffic, according to Caltrans data. On a road that busy, even a single collision can disrupt movement across the region.

The death lands in the middle of a broader public-safety crisis the city has already put on paper. The City of Fresno adopted its Vision Zero Action Plan on May 21, 2026, saying the city faces 217 fatal crashes and 629 severe injury crashes on city streets. City planning documents say Fresno averaged more than 40 traffic deaths and 125 severe injuries a year between 2019 and 2023, with pedestrians accounting for more than 280 deaths or severe injuries over that period.
Those numbers give added weight to the city’s 2024 Active Transportation Plan, which updates earlier efforts to improve accessibility, safety and connectivity for people walking, biking, using wheelchairs or traveling by other human-powered means. The fatal crash on the Highway 99 overpass adds another data point to a pattern Fresno officials have already acknowledged: dangerous streets, vulnerable pedestrians and a transportation network where one bad collision can choke a major artery in seconds.
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