NYU Langone plans major hospital campus in Melville, near Suffolk border

NYU Langone’s plan for a sprawling hospital campus in Melville puts one of Long Island’s biggest health care bets right at the Suffolk border, where it could redraw how patients move between emergency rooms, inpatient beds and specialist offices. The project would rise on a 45-acre parcel at the Huntington Quadrangle, just southeast of the Long Island Expressway and New York State Route 110, a location that ties the campus directly to the traffic patterns many Suffolk families already use for care.

The system said it bought the property on May 21 for $135.5 million and announced the project on June 2. Its design calls for more than 500 private inpatient rooms, 70 emergency department bays, operating and procedure suites with diagnostic imaging, scientific research space and room for the NYU Grossman Long Island School of Medicine. NYU Langone described the development as more than one million square feet and said it would be Long Island’s first new hospital since 1980.

For Suffolk patients, the scale matters because this is not a small outpatient annex. A new academic medical center of this size would compete directly for patients who now depend on existing hospital systems in eastern and central Long Island, including NYU Langone Hospital-Suffolk in Patchogue and Stony Brook University Hospital. The Melville campus could also affect where people go for trauma-level emergency coverage, complex procedures and follow-up specialty care, especially if its ER and surgical capacity pull more cases west toward Nassau County.

NYU Langone said the project could generate up to 8,000 union construction jobs, 2,500 indirect jobs and thousands of permanent jobs once the campus opens. That kind of workforce growth would ripple beyond the hospital itself, bringing more ambulance runs, worker commutes, parking demand and service-sector activity to the already busy Route 110 corridor. The system also said it will maintain a strong presence in Mineola during construction and beyond, signaling that Melville would expand its Long Island footprint rather than replace the 591-bed NYU Langone Hospital-Long Island.

The medical school moving with the project adds another layer. NYU Grossman Long Island School of Medicine is the country’s only three-year, tuition-free medical degree focused on primary care, and relocating it to Melville would deepen the area’s role as a training site for physicians and researchers. For Suffolk, that could mean more academic medicine nearby, but also a bigger contest for patients, specialists and referrals as Long Island’s hospital systems keep consolidating and repositioning themselves around the border. The project still needs extensive state and local approvals before any ground is broken.