NYU Langone opens new ambulatory care center in downtown Patchogue

NYU Langone opened its new ambulatory care center at 196 East Main Street in downtown Patchogue, turning the former Burlington store into a 54,000-square-foot medical site with six operating rooms and 22 recovery bays. The center is built for outpatient surgery in orthopedic surgery, colorectal surgery, gynecologic surgery, pain management, plastic surgery and urologic surgery, bringing those appointments closer to Suffolk patients who would otherwise travel farther for care.

Before Burlington, the property housed BeeHive and then Mid-Island Department Store for decades. NYU Langone bought the site in 2022 after Burlington moved to Gateway Plaza on Sunrise Highway, and the plan from the start was to replace a vacant retail box with a surgical center and physician offices. Patchogue Mayor Paul Pontieri said at the time that the project would "activate that end of town" and was "what Main Street needed."

East Main Street now includes patients, staff and post-op visits alongside shops and restaurants. The facility was designed with collaboration from local artists. Surgeons from nearby NYU Langone Hospital-Suffolk had already begun using the operating rooms before the center reached full operating mode.

In July 2025, NYU Langone expanded outpatient services in Middle Island and Patchogue with primary care, cardiology, general and bariatric surgery and plastic surgery. Andrew Rubin, a senior vice president at the health system, said the mission was to "bring world-class care to where our patients live and work."

NYU Langone Hospital-Suffolk, a 306-bed medical center in Patchogue, is the emergency department entry point for the health system’s provisional Level 2 trauma center and serves as its easternmost hospital and seventh hospital overall. The hospital became part of NYU Langone after the Long Island Community Hospital merger was completed in March 2025, and the expansion added robotic surgery and gynecologic oncology. NYU Langone’s broader Long Island plans also include an academic medical center in Melville and an ambulatory surgery center in Manhasset later this year.